Obesity and diabetes can be epigenetically inherited from parents

It’s all genetics

Biotechin.Asia

You Are What Your Parents Ate!

csm_Fotolia_Crevis_75956095_M_b782bcd524 “The results showed that both oocytes and sperm passed on epigenetic information, which particularly in the female offspring led to severe obesity,” said Prof. Johannes Beckers. (Photo: Fotolia/ cervis)

Diet-induced obesity and diabetes can be epigenetically* inherited by the offspring via both oocytes and sperm. Scientists from Technical University of Munich in collaboration with researchers at Helmholtz Zentrum München and the German Center for Diabetes Research (DZD) have shown that. The results were published in the journal Nature Genetics.

[*Epigenetics: In contrast to genetics, the term epigenetics refers to the inheritance of traits that are not determined in the primary sequence of the DNA (the genes). So far, RNA transcripts and chemical modifications of the chromatin (e.g. on the DNA or the histones) have been considered as carriers of this epigenetic information.]

For its studies, the team of the Institute of Experimental Genetics…

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